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Boosting nutrient starvation-dominated cancer therapy through curcumin-augmented mitochondrial Ca(2+) overload and obatoclax-mediated autophagy inhibition as supported by a novel nano-modulator GO-Alg@CaP/CO
BACKGROUND: By hindering energy supply pathway for cancer cells, an alternative therapeutic strategy modality is put forward: tumor starvation therapy. And yet only in this blockade of glucose supply which is far from enough to result in sheer apoptosis of cancer cells. RESULTS: In an effort to boos...
Autores principales: | Wang, Xuan, Li, Yunhao, Jia, Fan, Cui, Xinyue, Pan, Zian, Wu, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097046/ https://www.ncbi.nlm.nih.gov/pubmed/35551609 http://dx.doi.org/10.1186/s12951-022-01439-0 |
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