β-Amyloid in blood neuronal-derived extracellular vesicles is elevated in cognitively normal adults at risk of Alzheimer’s disease and predicts cerebral amyloidosis

BACKGROUND: Blood biomarkers that can be used for preclinical Alzheimer’s disease (AD) diagnosis would enable trial enrollment at a time when the disease is potentially reversible. Here, we investigated plasma neuronal-derived extracellular vesicle (nEV) cargo in patients along the Alzheimer’s conti...

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Detalles Bibliográficos
Autores principales: Li, Tao-Ran, Yao, Yun-Xia, Jiang, Xue-Yan, Dong, Qiu-Yue, Yu, Xian-Feng, Wang, Ting, Cai, Yan-Ning, Han, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097146/
https://www.ncbi.nlm.nih.gov/pubmed/35550625
http://dx.doi.org/10.1186/s13195-022-01010-x

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