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Reliable In Silico Ranking of Engineered Therapeutic TCR Binding Affinities with MMPB/GBSA

[Image: see text] Accurate and efficient in silico ranking of protein–protein binding affinities is useful for protein design with applications in biological therapeutics. One popular approach to rank binding affinities is to apply the molecular mechanics Poisson–Boltzmann/generalized Born surface a...

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Detalles Bibliográficos
Autores principales:	Crean, Rory M., Pudney, Christopher R., Cole, David K., van der Kamp, Marc W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097153/ https://www.ncbi.nlm.nih.gov/pubmed/35049312 http://dx.doi.org/10.1021/acs.jcim.1c00765

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