Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes

Correct segregation of chromosomes during mitosis is essential to prevent aneuploidy. In this issue, Ferrandiz et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202203021) show that endomembranes can promote chromosome missegregation by “ensheathing” misaligned chromosomes, preventing their in...

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Detalles Bibliográficos
Autores principales: Donker, Lisa, Godinho, Susana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097545/
https://www.ncbi.nlm.nih.gov/pubmed/35536317
http://dx.doi.org/10.1083/jcb.202204114
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author Donker, Lisa
Godinho, Susana A.
author_facet Donker, Lisa
Godinho, Susana A.
author_sort Donker, Lisa
collection PubMed
description Correct segregation of chromosomes during mitosis is essential to prevent aneuploidy. In this issue, Ferrandiz et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202203021) show that endomembranes can promote chromosome missegregation by “ensheathing” misaligned chromosomes, preventing their integration into the metaphase plate. Their findings point toward endomembranes as a potential risk factor for aneuploidy.
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spelling pubmed-90975452022-12-06 Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes Donker, Lisa Godinho, Susana A. J Cell Biol Spotlight Correct segregation of chromosomes during mitosis is essential to prevent aneuploidy. In this issue, Ferrandiz et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202203021) show that endomembranes can promote chromosome missegregation by “ensheathing” misaligned chromosomes, preventing their integration into the metaphase plate. Their findings point toward endomembranes as a potential risk factor for aneuploidy. Rockefeller University Press 2022-05-10 /pmc/articles/PMC9097545/ /pubmed/35536317 http://dx.doi.org/10.1083/jcb.202204114 Text en © 2022 Donker and Godinho https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Donker, Lisa
Godinho, Susana A.
Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes
title Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes
title_full Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes
title_fullStr Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes
title_full_unstemmed Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes
title_short Too close for comfort? Endomembranes promote missegregation by enclosing lost chromosomes
title_sort too close for comfort? endomembranes promote missegregation by enclosing lost chromosomes
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097545/
https://www.ncbi.nlm.nih.gov/pubmed/35536317
http://dx.doi.org/10.1083/jcb.202204114
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