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Cerebrospinal Fluid Cell-Free DNA-Based Detection of High Level of Genomic Instability Is Associated With Poor Prognosis in NSCLC Patients With Leptomeningeal Metastases

INTRODUCTION: Leptomeningeal metastasis (LM) commonly occurs in non-small cell lung cancer (NSCLC) patients and has a poor prognosis. Due to limited access to leptomeningeal lesions, the genetic characteristics of LM have not been explored to date. Cerebrospinal fluid (CSF) may be the most represent...

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Detalles Bibliográficos
Autores principales:	Wu, Xi, Xing, Puyuan, Shi, Min, Guo, Weihua, Zhao, Fangping, Zhu, Honglin, Xiao, Jianping, Wan, Jinghai, Li, Junling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097599/ https://www.ncbi.nlm.nih.gov/pubmed/35574310 http://dx.doi.org/10.3389/fonc.2022.664420

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