Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat

OBJECTIVE: Classical ATP-independent non-shivering thermogenesis enabled by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is activated, but not essential for survival, in the cold. It has long been suspected that futile ATP-consuming substrate cycles also contribute to thermogenesis and...

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Detalles Bibliográficos
Autores principales: Oeckl, Josef, Janovska, Petra, Adamcova, Katerina, Bardova, Kristina, Brunner, Sarah, Dieckmann, Sebastian, Ecker, Josef, Fromme, Tobias, Funda, Jiri, Gantert, Thomas, Giansanti, Piero, Hidrobo, Maria Soledad, Kuda, Ondrej, Kuster, Bernhard, Li, Yongguo, Pohl, Radek, Schmitt, Sabine, Schweizer, Sabine, Zischka, Hans, Zouhar, Petr, Kopecky, Jan, Klingenspor, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097615/
https://www.ncbi.nlm.nih.gov/pubmed/35470094
http://dx.doi.org/10.1016/j.molmet.2022.101499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097615/
https://www.ncbi.nlm.nih.gov/pubmed/35470094
http://dx.doi.org/10.1016/j.molmet.2022.101499

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