TRAP1 regulates the response of colorectal cancer cells to hypoxia and inhibits ribosome biogenesis under conditions of oxygen deprivation

Metabolic rewiring fuels rapid cancer cell proliferation by promoting adjustments in energetic resources, and increasing glucose uptake and its conversion into lactate, even in the presence of oxygen. Furthermore, solid tumors often contain hypoxic areas and can rapidly adapt to low oxygen condition...

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Detalles Bibliográficos
Autores principales: Bruno, Giuseppina, Bergolis, Valeria Li, Piscazzi, Annamaria, Crispo, Fabiana, Condelli, Valentina, Zoppoli, Pietro, Maddalena, Francesca, Pietrafesa, Michele, Giordano, Guido, Matassa, Danilo Swann, Esposito, Franca, Landriscina, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097768/
https://www.ncbi.nlm.nih.gov/pubmed/35543151
http://dx.doi.org/10.3892/ijo.2022.5369

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