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Dezocine is a Biased Ligand without Significant Beta-Arrestin Activation of the mu Opioid Receptor

Dezocine is an opioid that was used in clinical practice for acute pain management in the US (1986 to 2011) and is currently in use in China. It is not listed as a controlled substance in the US due to no reported cases of addiction. Dezocine is a partial agonist at the mu opioid receptor (MOR); how...

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Detalles Bibliográficos
Autores principales: Grothusen, John, Lin, Wenzhen, Xi, Jin, Zanni, Giulia, Barr, Gordon A., Liu, Renyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097853/
https://www.ncbi.nlm.nih.gov/pubmed/35572183

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