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SARS-CoV-2 epitope-specific CD4(+) memory T cell responses across COVID-19 disease severity and antibody durability

CD4(+) T cells are central to long-term immunity against viruses through the functions of T helper-1 (Th1) and T follicular helper (Tfh) cell subsets. To better understand the role of these subsets in COVID-19 immunity, we conducted a longitudinal study of SARS-CoV-2-specific CD4(+) T cell and antib...

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Detalles Bibliográficos
Autores principales: Nelson, Ryan W., Chen, Yuezhou, Venezia, Olivia L., Majerus, Richard M, Shin, Daniel S., Carrington, Mary N., Yu, Xu G., Wesemann, Duane R., Moon, James J., Luster, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097883/
https://www.ncbi.nlm.nih.gov/pubmed/35857584
http://dx.doi.org/10.1126/sciimmunol.abl9464