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Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma
The tumor microenvironment (TME) plays a pivotal role in establishing malignancy, and it is associated with high glycolytic metabolism and lactate release through monocarboxylate transporters (MCTs). Several lines of evidence suggest that lactate also serves as a signaling molecule through its recep...
Autores principales: | Longhitano, Lucia, Vicario, Nunzio, Tibullo, Daniele, Giallongo, Cesarina, Broggi, Giuseppe, Caltabiano, Rosario, Barbagallo, Giuseppe Maria Vincenzo, Altieri, Roberto, Baghini, Marta, Di Rosa, Michelino, Parenti, Rosalba, Giordano, Antonio, Mione, Maria Caterina, Li Volti, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097945/ https://www.ncbi.nlm.nih.gov/pubmed/35574309 http://dx.doi.org/10.3389/fonc.2022.871798 |
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