Cargando…
Efficacy versus abundancy: Comparing vaccination schemes
We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and rate of deployment of low efficacy vaccines lowers the cumul...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097986/ https://www.ncbi.nlm.nih.gov/pubmed/35552553 http://dx.doi.org/10.1371/journal.pone.0267840 |
_version_ | 1784706280530640896 |
---|---|
author | El Deeb, Omar Jalloul, Maya |
author_facet | El Deeb, Omar Jalloul, Maya |
author_sort | El Deeb, Omar |
collection | PubMed |
description | We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and rate of deployment of low efficacy vaccines lowers the cumulative number of deaths in comparison to slower deployment of high efficacy vaccines. We also forecast that, at the same daily deployment rate, the earlier introduction of vaccination schemes with lower efficacy would also lower the number of deaths with respect to a delayed introduction of high efficacy vaccines, which can however, still achieve lower numbers of infections and better herd immunity. |
format | Online Article Text |
id | pubmed-9097986 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-90979862022-05-13 Efficacy versus abundancy: Comparing vaccination schemes El Deeb, Omar Jalloul, Maya PLoS One Research Article We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and rate of deployment of low efficacy vaccines lowers the cumulative number of deaths in comparison to slower deployment of high efficacy vaccines. We also forecast that, at the same daily deployment rate, the earlier introduction of vaccination schemes with lower efficacy would also lower the number of deaths with respect to a delayed introduction of high efficacy vaccines, which can however, still achieve lower numbers of infections and better herd immunity. Public Library of Science 2022-05-12 /pmc/articles/PMC9097986/ /pubmed/35552553 http://dx.doi.org/10.1371/journal.pone.0267840 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication. |
spellingShingle | Research Article El Deeb, Omar Jalloul, Maya Efficacy versus abundancy: Comparing vaccination schemes |
title | Efficacy versus abundancy: Comparing vaccination schemes |
title_full | Efficacy versus abundancy: Comparing vaccination schemes |
title_fullStr | Efficacy versus abundancy: Comparing vaccination schemes |
title_full_unstemmed | Efficacy versus abundancy: Comparing vaccination schemes |
title_short | Efficacy versus abundancy: Comparing vaccination schemes |
title_sort | efficacy versus abundancy: comparing vaccination schemes |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097986/ https://www.ncbi.nlm.nih.gov/pubmed/35552553 http://dx.doi.org/10.1371/journal.pone.0267840 |
work_keys_str_mv | AT eldeebomar efficacyversusabundancycomparingvaccinationschemes AT jalloulmaya efficacyversusabundancycomparingvaccinationschemes |