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Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial
BACKGROUND: BCG vaccination prevents severe childhood tuberculosis (TB) and was introduced in South Africa in the 1950s. It is hypothesised that BCG trains the innate immune system by inducing epigenetic and functional reprogramming, thus providing non-specific protection from respiratory tract infe...
Autores principales: | Upton, Caryn M., van Wijk, Rob C., Mockeliunas, Laurynas, Simonsson, Ulrika S.H., McHarry, Kirsten, van den Hoogen, Gerben, Muller, Chantal, von Delft, Arné, van der Westhuizen, Helene-Mari, van Crevel, Reinout, Walzl, Gerhard, Baptista, Pedro M., Peter, Jonathan, Diacon, Andreas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098089/ https://www.ncbi.nlm.nih.gov/pubmed/35582122 http://dx.doi.org/10.1016/j.eclinm.2022.101414 |
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