Heat shock induces premature transcript termination and reconfigures the human transcriptome

The heat shock (HS) response involves rapid induction of HS genes, whereas transcriptional repression is established more slowly at most other genes. Previous data suggested that such repression results from inhibition of RNA polymerase II (RNAPII) pause release, but here, we show that HS strongly a...

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Detalles Bibliográficos
Autores principales: Cugusi, Simona, Mitter, Richard, Kelly, Gavin P., Walker, Jane, Han, Zhong, Pisano, Paola, Wierer, Michael, Stewart, Aengus, Svejstrup, Jesper Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098121/
https://www.ncbi.nlm.nih.gov/pubmed/35114099
http://dx.doi.org/10.1016/j.molcel.2022.01.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098121/
https://www.ncbi.nlm.nih.gov/pubmed/35114099
http://dx.doi.org/10.1016/j.molcel.2022.01.007

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