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FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells

Tyrosine phosphorylation, orchestrated by tyrosine kinases and phosphatases, modulates a multi-layered signaling network in a time- and space-dependent manner. Dysregulation of this post-translational modification is inevitably associated with pathological diseases. Our previous work has demonstrate...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanchun, Xiong, Xuexue, Zhu, Qi, Zhang, Jiali, Chen, Shengmiao, Wang, Yuetong, Cao, Jian, Chen, Li, Hou, Linjun, Zhao, Xi, Hao, Piliang, Chen, Jian, Zhuang, Min, Li, Dake, Fan, Gaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098222/ https://www.ncbi.nlm.nih.gov/pubmed/35550247 http://dx.doi.org/10.7554/eLife.76183

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