Cracking the cryptic code in amyotrophic lateral sclerosis and frontotemporal dementia: Towards therapeutic targets and biomarkers

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating human neurodegenerative diseases. A hallmark pathological feature of both diseases is the depletion of the RNA‐binding protein TDP‐43 from the nucleus in the brain and spinal cord of patients. A major function...

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Detalles Bibliográficos
Autores principales: Akiyama, Tetsuya, Koike, Yuka, Petrucelli, Leonard, Gitler, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098226/
https://www.ncbi.nlm.nih.gov/pubmed/35567447
http://dx.doi.org/10.1002/ctm2.818

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