Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS

The “obesity paradox in acute respiratory distress syndrome” (ARDS) refers to the phenomenon in which obesity is associated with higher morbidity but lower mortality in patients with ARDS. Endothelial-to-mesenchymal transition (EndMT) represents a key link in the interaction between endothelial disr...

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Detalles Bibliográficos
Autores principales: Qi, Di, Deng, Wang, Chen, Xiaorui, Fan, Shulei, Peng, Junnan, Tang, Xumao, Wang, Daoxin, Yu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098334/
https://www.ncbi.nlm.nih.gov/pubmed/35571250
http://dx.doi.org/10.1155/2022/5475832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098334/
https://www.ncbi.nlm.nih.gov/pubmed/35571250
http://dx.doi.org/10.1155/2022/5475832

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