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Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS
The “obesity paradox in acute respiratory distress syndrome” (ARDS) refers to the phenomenon in which obesity is associated with higher morbidity but lower mortality in patients with ARDS. Endothelial-to-mesenchymal transition (EndMT) represents a key link in the interaction between endothelial disr...
Autores principales: | Qi, Di, Deng, Wang, Chen, Xiaorui, Fan, Shulei, Peng, Junnan, Tang, Xumao, Wang, Daoxin, Yu, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098334/ https://www.ncbi.nlm.nih.gov/pubmed/35571250 http://dx.doi.org/10.1155/2022/5475832 |
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