Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation

The NLRP3 inflammasome is linked to sterile and pathogen-dependent inflammation, and its dysregulation underlies many chronic diseases. Mitochondria have been implicated as regulators of the NLRP3 inflammasome through several mechanisms including generation of mitochondrial reactive oxygen species (...

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Detalles Bibliográficos
Autores principales: Billingham, Leah K., Stoolman, Joshua S., Vasan, Karthik, Rodriguez, Arianne E., Poor, Taylor A., Szibor, Marten, Jacobs, Howard T., Reczek, Colleen R., Rashidi, Aida, Zhang, Peng, Miska, Jason, Chandel, Navdeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098388/
https://www.ncbi.nlm.nih.gov/pubmed/35484407
http://dx.doi.org/10.1038/s41590-022-01185-3

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