Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration

Silicosis is the most prevalent and fatal occupational disease with no effective therapeutics, and currently used drugs cannot reverse the disease progress. Worse still, there are still challenges to be addressed to fully decipher the intricated pathogenesis. Thus, specifying the essential mechanism...

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Detalles Bibliográficos
Autores principales: Wang, Mingyao, Zhang, Zhe, Liu, Jiangfeng, Song, Meiyue, Zhang, Tiantian, Chen, Yiling, Hu, Huiyuan, Yang, Peiran, Li, Bolun, Song, Xiaomin, Pang, Junling, Xing, Yanjiang, Cao, Zhujie, Guo, Wenjun, Yang, Hao, Wang, Jing, Yang, Juntao, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098425/
https://www.ncbi.nlm.nih.gov/pubmed/35551173
http://dx.doi.org/10.1038/s41392-022-00959-3

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