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Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes

Emerging evidence points towards a regulatory role of the circadian clock in alternative splicing (AS). Whether alterations in core-clock components may contribute to differential AS events is largely unknown. To address this, we carried out a computational analysis on recently generated time-series...

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Detalles Bibliográficos
Autores principales: Malhan, Deeksha, Basti, Alireza, Relógio, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098426/
https://www.ncbi.nlm.nih.gov/pubmed/35552415
http://dx.doi.org/10.1038/s41540-022-00225-w

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