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The impact of pitolisant, an H(3) receptor antagonist/inverse agonist, on perirhinal cortex activity in individual neuron and neuronal population levels

Histamine is a neurotransmitter that modulates neuronal activity and regulates various brain functions. Histamine H(3) receptor (H(3)R) antagonists/inverse agonists enhance its release in most brain regions, including the cerebral cortex, which improves learning and memory and exerts an antiepilepti...

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Detalles Bibliográficos
Autores principales: Hirano, Kyosuke, Morishita, Yoshikazu, Minami, Masabumi, Nomura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098477/
https://www.ncbi.nlm.nih.gov/pubmed/35551460
http://dx.doi.org/10.1038/s41598-022-11032-y