The kinesin Eg5 inhibitor K858 exerts antiproliferative and proapoptotic effects and attenuates the invasive potential of head and neck squamous carcinoma cells

Our group recently demonstrated that K858, an inhibitor of motor kinesin Eg5, has important antiproliferative and apoptotic effects on breast cancer, prostatic cancer, melanoma and glioblastoma cells. Since high levels of kinesin Eg5 expression have been correlated with a poor prognosis in laryngeal...

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Detalles Bibliográficos
Autores principales: Nicolai, Alice, Taurone, Samanta, Carradori, Simone, Artico, Marco, Greco, Antonio, Costi, Roberta, Scarpa, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098576/
https://www.ncbi.nlm.nih.gov/pubmed/35312942
http://dx.doi.org/10.1007/s10637-022-01238-2

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