Isoflurane and Sevoflurane Induce Cognitive Impairment in Neonatal Rats by Inhibiting Neural Stem Cell Development Through Microglial Activation, Neuroinflammation, and Suppression of VEGFR2 Signaling Pathway

Inhaled anesthetics are known to induce neurotoxicity in the developing brains of rodents, although the mechanisms are not well understood. The aim of this study was to elucidate the molecular mechanisms underlying anesthetics-induced neurodevelopmental toxicity by VEGF receptor 2 (VEGFR2) through t...

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Detalles Bibliográficos
Autores principales: Zuo, Chunlong, Ma, Junmei, Pan, Yizhao, Zheng, Dongxu, Chen, Chunjiang, Ruan, Naqi, Su, Ying, Nan, Haihan, Lian, Qingquan, Lin, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098611/
https://www.ncbi.nlm.nih.gov/pubmed/35471722
http://dx.doi.org/10.1007/s12640-022-00511-9

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