Mechanical loading of intraluminal pressure mediates wound angiogenesis by regulating the TOCA family of F-BAR proteins

Angiogenesis is regulated in coordinated fashion by chemical and mechanical cues acting on endothelial cells (ECs). However, the mechanobiological mechanisms of angiogenesis remain unknown. Herein, we demonstrate a crucial role of blood flow-driven intraluminal pressure (IP) in regulating wound angi...

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Detalles Bibliográficos
Autores principales: Yuge, Shinya, Nishiyama, Koichi, Arima, Yuichiro, Hanada, Yasuyuki, Oguri-Nakamura, Eri, Hanada, Sanshiro, Ishii, Tomohiro, Wakayama, Yuki, Hasegawa, Urara, Tsujita, Kazuya, Yokokawa, Ryuji, Miura, Takashi, Itoh, Toshiki, Tsujita, Kenichi, Mochizuki, Naoki, Fukuhara, Shigetomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098626/
https://www.ncbi.nlm.nih.gov/pubmed/35551172
http://dx.doi.org/10.1038/s41467-022-30197-8

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