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Clinical Observation of the Effects of Oral Opioid on Inflammatory Cytokines and Gut Microbiota in Patients with Moderate to Severe Cancer Pain: A Retrospective Cohort Study

INTRODUCTION: Recent studies have revealed that inflammation is a key factor in the causation of opioid analgesic tolerance. Opioids can induce a massive release of inflammatory cytokines and disruption of intestinal barrier function by activating Toll-like receptors 2/4 (TLR2/4), eventually resulti...

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Detalles Bibliográficos
Autores principales:	Wang, Hanxiang, Luo, Juan, Chen, Xu, Hu, Huiping, Li, Shijun, Zhang, Yu, Shi, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098777/ https://www.ncbi.nlm.nih.gov/pubmed/35435623 http://dx.doi.org/10.1007/s40122-022-00386-w

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