Metformin Alleviates Airway Hyperresponsiveness in a Mouse Model of Diet-Induced Obesity

Obese asthma is a unique phenotype of asthma characterized by non-allergic airway hyperresponsiveness (AHR) and inflammation which responds poorly to standard asthma therapy. Metformin is an oral hypoglycemic drug with insulin-sensitizing and anti-inflammatory properties. The objective of the curren...

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Detalles Bibliográficos
Autores principales: Gu, Chenjuan, Loube, Jeff, Lee, Rachel, Bevans-Fonti, Shannon, Wu, Tianshi David, Barmine, Jessica H., Jun, Jonathan C., McCormack, Meredith C., Hansel, Nadia N., Mitzner, Wayne, Polotsky, Vsevolod Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098833/
https://www.ncbi.nlm.nih.gov/pubmed/35574481
http://dx.doi.org/10.3389/fphys.2022.883275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098833/
https://www.ncbi.nlm.nih.gov/pubmed/35574481
http://dx.doi.org/10.3389/fphys.2022.883275

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