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Metformin Alleviates Airway Hyperresponsiveness in a Mouse Model of Diet-Induced Obesity

Obese asthma is a unique phenotype of asthma characterized by non-allergic airway hyperresponsiveness (AHR) and inflammation which responds poorly to standard asthma therapy. Metformin is an oral hypoglycemic drug with insulin-sensitizing and anti-inflammatory properties. The objective of the curren...

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Detalles Bibliográficos
Autores principales:	Gu, Chenjuan, Loube, Jeff, Lee, Rachel, Bevans-Fonti, Shannon, Wu, Tianshi David, Barmine, Jessica H., Jun, Jonathan C., McCormack, Meredith C., Hansel, Nadia N., Mitzner, Wayne, Polotsky, Vsevolod Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098833/ https://www.ncbi.nlm.nih.gov/pubmed/35574481 http://dx.doi.org/10.3389/fphys.2022.883275

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