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Molecular basis for inhibiting human glucose transporters by exofacial inhibitors

Human glucose transporters (GLUTs) are responsible for cellular uptake of hexoses. Elevated expression of GLUTs, particularly GLUT1 and GLUT3, is required to fuel the hyperproliferation of cancer cells, making GLUT inhibitors potential anticancer therapeutics. Meanwhile, GLUT inhibitor-conjugated in...

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Detalles Bibliográficos
Autores principales:	Wang, Nan, Zhang, Shuo, Yuan, Yafei, Xu, Hanwen, Defossa, Elisabeth, Matter, Hans, Besenius, Melissa, Derdau, Volker, Dreyer, Matthias, Halland, Nis, He, Kaihui Hu, Petry, Stefan, Podeschwa, Michael, Tennagels, Norbert, Jiang, Xin, Yan, Nieng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098912/ https://www.ncbi.nlm.nih.gov/pubmed/35552392 http://dx.doi.org/10.1038/s41467-022-30326-3

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