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Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model

Understanding the mechanisms behind chemical susceptibility differences is key to protecting sensitive populations. However, elucidating gene-environment interactions (GxE) presents a daunting challenge. While mammalian models have proven useful, problems with scalability to an enormous chemical exp...

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Detalles Bibliográficos
Autores principales: Wallis, Dylan J., La Du, Jane, Thunga, Preethi, Elson, Daniel, Truong, Lisa, Kolluri, Siva K., Tanguay, Robyn L., Reif, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098949/
https://www.ncbi.nlm.nih.gov/pubmed/35573279
http://dx.doi.org/10.3389/ftox.2022.846221