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Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model
Understanding the mechanisms behind chemical susceptibility differences is key to protecting sensitive populations. However, elucidating gene-environment interactions (GxE) presents a daunting challenge. While mammalian models have proven useful, problems with scalability to an enormous chemical exp...
Autores principales: | Wallis, Dylan J., La Du, Jane, Thunga, Preethi, Elson, Daniel, Truong, Lisa, Kolluri, Siva K., Tanguay, Robyn L., Reif, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098949/ https://www.ncbi.nlm.nih.gov/pubmed/35573279 http://dx.doi.org/10.3389/ftox.2022.846221 |
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