PreS/2-21-Guided siRNA Nanoparticles Target to Inhibit Hepatitis B Virus Infection and Replication

A viable therapy is needed to overcome the deadlock of the incurable chronic hepatitis B (CHB). The prolonged existence of covalently closed circular DNA (cccDNA) and integrated HBV DNA in the nucleus of hepatocytes is the root cause of CHB. As a result, it is critical to successfully suppress HBV D...

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Detalles Bibliográficos
Autores principales: Gao, Lixia, Yang, Jie, Feng, Jutao, Liu, Ziying, Dong, Ying, Luo, Jiangyan, Yu, Liangzhentian, Wang, Jiamei, Fan, Hongying, Ma, Weifeng, Liu, Tiancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098953/
https://www.ncbi.nlm.nih.gov/pubmed/35572586
http://dx.doi.org/10.3389/fimmu.2022.856463

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