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Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma
Optic pathway glioma (OPG) is a rare tumor located in optic nerve, optic tract, or optic chiasm. Treatment options for OPG include surgery, radiation therapy (RT), and chemotherapy. Although RT may provide favorable long-term outcomes in manner of either adjuvant or salvage aim, chemotherapy-first a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098980/ https://www.ncbi.nlm.nih.gov/pubmed/35545828 http://dx.doi.org/10.14791/btrt.2022.0003 |
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author | Kim, Nalee Lim, Do Hoon |
author_facet | Kim, Nalee Lim, Do Hoon |
author_sort | Kim, Nalee |
collection | PubMed |
description | Optic pathway glioma (OPG) is a rare tumor located in optic nerve, optic tract, or optic chiasm. Treatment options for OPG include surgery, radiation therapy (RT), and chemotherapy. Although RT may provide favorable long-term outcomes in manner of either adjuvant or salvage aim, chemotherapy-first approach is increasingly performed due to possible late effects of RT. Proton beam RT may allow normal tissue sparing of radiation exposure compared to conventional X-ray treatment. Therefore, proton beam RT is expected to reduce complications from RT. This review discusses the recent updates on oncologic outcomes of OPG, late toxicities following RT, and compares the outcomes between X-ray treatment and proton beam RT. |
format | Online Article Text |
id | pubmed-9098980 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology |
record_format | MEDLINE/PubMed |
spelling | pubmed-90989802022-05-19 Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma Kim, Nalee Lim, Do Hoon Brain Tumor Res Treat Review Article Optic pathway glioma (OPG) is a rare tumor located in optic nerve, optic tract, or optic chiasm. Treatment options for OPG include surgery, radiation therapy (RT), and chemotherapy. Although RT may provide favorable long-term outcomes in manner of either adjuvant or salvage aim, chemotherapy-first approach is increasingly performed due to possible late effects of RT. Proton beam RT may allow normal tissue sparing of radiation exposure compared to conventional X-ray treatment. Therefore, proton beam RT is expected to reduce complications from RT. This review discusses the recent updates on oncologic outcomes of OPG, late toxicities following RT, and compares the outcomes between X-ray treatment and proton beam RT. The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology 2022-04 2022-04-29 /pmc/articles/PMC9098980/ /pubmed/35545828 http://dx.doi.org/10.14791/btrt.2022.0003 Text en Copyright © 2022 The Korean Brain Tumor Society, The Korean Society for Neuro-Oncology, and The Korean Society for Pediatric Neuro-Oncology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kim, Nalee Lim, Do Hoon Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma |
title | Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma |
title_full | Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma |
title_fullStr | Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma |
title_full_unstemmed | Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma |
title_short | Recent Updates on Radiation Therapy for Pediatric Optic Pathway Glioma |
title_sort | recent updates on radiation therapy for pediatric optic pathway glioma |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098980/ https://www.ncbi.nlm.nih.gov/pubmed/35545828 http://dx.doi.org/10.14791/btrt.2022.0003 |
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