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Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma

Lung cancer is a common disease with a poor prognosis. Genomic alterations involving the KRAS gene are common in lung carcinomas, although much is unknown about how different mutations, deletions, and expressions influence the disease course. The first approval of a KRAS-directed inhibitor was recen...

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Detalles Bibliográficos
Autores principales: Khadse, Anand, Haakensen, Vilde D., Silwal-Pandit, Laxmi, Hamfjord, Julian, Micke, Patrick, Botling, Johan, Brustugun, Odd Terje, Lingjærde, Ole Christian, Helland, Åslaug, Kure, Elin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098994/
https://www.ncbi.nlm.nih.gov/pubmed/35574381
http://dx.doi.org/10.3389/fonc.2022.873532