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New insights into IRE1α activation and function in anti-tumor immunity
Logue, Gorman, and Samali highlight a study by Guttman and colleagues (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202111068) that shows exogenous antigen peptides imported into the ER can activate the ER stress sensor IRE1α, attenuating cross-presentation by dendritic cells.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099116/ https://www.ncbi.nlm.nih.gov/pubmed/35544036 http://dx.doi.org/10.1083/jcb.202205019 |