Utility of the (13)C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children

The (13)C‐pantoprazole breath test (PAN‐BT) is a safe, noninvasive, in vivo CYP2C19 phenotyping probe for adults. Our objective was to evaluate PAN‐BT performance in children, with a focus on discriminating individuals who, according to guidelines from the Clinical Pharmacology Implementation Consor...

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Detalles Bibliográficos
Autores principales: Feldman, Keith, Kearns, Gregory L., Pearce, Robin E., Abdel‐Rahman, Susan M., Steven Leeder, James, Friesen, Alec, Staggs, Vincent S., Gaedigk, Andrea, Weigel, Jaylene, Shakhnovich, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099127/
https://www.ncbi.nlm.nih.gov/pubmed/35099109
http://dx.doi.org/10.1111/cts.13232

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