Human Proteinase 3, an important autoantigen of c-ANCA associated vasculitis, shares cross-reactive epitopes with serine protease allergens from mites: an in silico analysis

Background: In autoimmune vasculitis, autoantibodies to Human Proteinase 3 (PR3), a human serine protease, seems to have a role on the inception of c-ANCA associated vasculitis. The origin of this autoreactive response remains unclear. However, for several autoreactive responses, molecular mimicry b...

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Detalles Bibliográficos
Autores principales: Buendía, Emiro, Marlon, Múnera, Parra, Orlando, Sánchez, María, Sánchez, Andrés, Sánchez, Jorge, Viasus, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099154/
https://www.ncbi.nlm.nih.gov/pubmed/35602671
http://dx.doi.org/10.12688/f1000research.28225.2

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