Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation

High-throughput (HT) in vitro to in vivo extrapolation (IVIVE) is an integral component in new approach method (NAM)-based risk assessment paradigms, for rapidly translating in vitro toxicity assay results into the context of in vivo exposure. When coupled with rapid exposure predictions, HT-IVIVE s...

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Detalles Bibliográficos
Autores principales: Moreau, Marjory, Mallick, Pankajini, Smeltz, Marci, Haider, Saad, Nicolas, Chantel I., Pendse, Salil N., Leonard, Jeremy A., Linakis, Matthew W., McMullen, Patrick D., Clewell, Rebecca A., Clewell, Harvey J., Yoon, Miyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099212/
https://www.ncbi.nlm.nih.gov/pubmed/35573278
http://dx.doi.org/10.3389/ftox.2022.894569

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