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Toward Novel [(18)F]Fluorine-Labeled Radiotracers for the Imaging of α-Synuclein Fibrils

The accumulation of α-synuclein aggregates (α-syn) in the human brain is an occurrence common to all α-synucleinopathies. Non-invasive detection of these aggregates in a living brain with a target-specific radiotracer is not yet possible. We have recently discovered that the inclusion of a methylene...

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Detalles Bibliográficos
Autores principales: Uzuegbunam, Bright C., Li, Junhao, Paslawski, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Yousefi, Behrooz Hooshyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099256/
https://www.ncbi.nlm.nih.gov/pubmed/35572127
http://dx.doi.org/10.3389/fnagi.2022.830704