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Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance

Heterochromatin is characterized by dimethylated or trimethylated histone H3 Lys9 (H3K9me2 or H3K9me3, respectively) and is found at transposable elements, satellite repeats and genes, where it ensures their transcriptional silencing. The histone methyltransferases (HMTs) that methylate H3K9 — in ma...

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Detalles Bibliográficos
Autores principales: Padeken, Jan, Methot, Stephen P., Gasser, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099300/
https://www.ncbi.nlm.nih.gov/pubmed/35562425
http://dx.doi.org/10.1038/s41580-022-00483-w

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