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Mechanistic and Therapeutic Insights into Ataxic Disorders with Pentanucleotide Expansions
Pentanucleotide expansion diseases constitute a special class of neurodegeneration. The repeat expansions occur in non-coding regions, have likely arisen from Alu elements, and often result in autosomal dominant or recessive phenotypes with underlying cerebellar neuropathology. When transcribed (pot...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099484/ https://www.ncbi.nlm.nih.gov/pubmed/35563872 http://dx.doi.org/10.3390/cells11091567 |