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Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study
Hypervirulent Klebsiella pneumoniae (hvKp) is an important strain that can cause multiple organ infections. Although hvKp infection cases are increasing, there is limited information on the prostatic abscesses caused by K. pneumoniae. Furthermore, the clinical significance of hvKp associated with K1...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099488/ https://www.ncbi.nlm.nih.gov/pubmed/35566647 http://dx.doi.org/10.3390/jcm11092521 |
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author | Hwang, Joo-Hee Hwang, Jeong-Hwan Lee, Seung Yeob Lee, Jaehyeon |
author_facet | Hwang, Joo-Hee Hwang, Jeong-Hwan Lee, Seung Yeob Lee, Jaehyeon |
author_sort | Hwang, Joo-Hee |
collection | PubMed |
description | Hypervirulent Klebsiella pneumoniae (hvKp) is an important strain that can cause multiple organ infections. Although hvKp infection cases are increasing, there is limited information on the prostatic abscesses caused by K. pneumoniae. Furthermore, the clinical significance of hvKp associated with K1 or K2 capsular types or virulence genes in prostatic abscesses remains unclear. Therefore, we aimed to elucidate the clinical and microbiological characteristics of prostatic abscesses caused by K. pneumoniae in relation to various virulence genes. A retrospective study was performed at a 1200-bed tertiary hospital between January 2014 and December 2019. Patients diagnosed with prostatic abscesses with K. pneumoniae isolated from blood, urine, pus, or tissue cultures were enrolled in this study. Our results demonstrate that 30.3% (10/33) of the prostatic abscesses were caused by K. pneumoniae. All strains isolated from patients with prostatic abscesses due to K. pneumoniae were the K1 capsular type, and eight patients (80.0%) carried rmpA and iutA genes that identified hvKp. These findings suggest that hvKp is an important pathogen in prostatic abscesses. Therefore, when treating patients with K. pneumoniae prostatic abscesses, attention should be paid to the characteristics of hvKp, such as bacteremia, multiorgan abscess formation, and metastatic spread. |
format | Online Article Text |
id | pubmed-9099488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90994882022-05-14 Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study Hwang, Joo-Hee Hwang, Jeong-Hwan Lee, Seung Yeob Lee, Jaehyeon J Clin Med Article Hypervirulent Klebsiella pneumoniae (hvKp) is an important strain that can cause multiple organ infections. Although hvKp infection cases are increasing, there is limited information on the prostatic abscesses caused by K. pneumoniae. Furthermore, the clinical significance of hvKp associated with K1 or K2 capsular types or virulence genes in prostatic abscesses remains unclear. Therefore, we aimed to elucidate the clinical and microbiological characteristics of prostatic abscesses caused by K. pneumoniae in relation to various virulence genes. A retrospective study was performed at a 1200-bed tertiary hospital between January 2014 and December 2019. Patients diagnosed with prostatic abscesses with K. pneumoniae isolated from blood, urine, pus, or tissue cultures were enrolled in this study. Our results demonstrate that 30.3% (10/33) of the prostatic abscesses were caused by K. pneumoniae. All strains isolated from patients with prostatic abscesses due to K. pneumoniae were the K1 capsular type, and eight patients (80.0%) carried rmpA and iutA genes that identified hvKp. These findings suggest that hvKp is an important pathogen in prostatic abscesses. Therefore, when treating patients with K. pneumoniae prostatic abscesses, attention should be paid to the characteristics of hvKp, such as bacteremia, multiorgan abscess formation, and metastatic spread. MDPI 2022-04-29 /pmc/articles/PMC9099488/ /pubmed/35566647 http://dx.doi.org/10.3390/jcm11092521 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hwang, Joo-Hee Hwang, Jeong-Hwan Lee, Seung Yeob Lee, Jaehyeon Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study |
title | Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study |
title_full | Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study |
title_fullStr | Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study |
title_full_unstemmed | Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study |
title_short | Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study |
title_sort | prostatic abscess caused by klebsiella pneumoniae: a 6-year single-center study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099488/ https://www.ncbi.nlm.nih.gov/pubmed/35566647 http://dx.doi.org/10.3390/jcm11092521 |
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