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Genetic Deficiency of Indoleamine 2,3-dioxygenase Aggravates Vascular but Not Liver Disease in a Nonalcoholic Steatohepatitis and Atherosclerosis Comorbidity Model

Nonalcoholic steatohepatitis (NASH) is a chronic liver disease that increases cardiovascular disease risk. Indoleamine 2,3-dioxygenase-1 (IDO1)-mediated tryptophan (Trp) metabolism has been proposed to play an immunomodulatory role in several diseases. The potential of IDO1 to be a link between NASH...

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Detalles Bibliográficos
Autores principales:	Arora, Aastha, Tripodi, Gustavo Luis, Kareinen, Ilona, Berg, Martin, Forteza, Maria Josefa, Gisterå, Anton, Griepke, Silke, Casagrande, Felipe Beccaria, Martins, Joilson O., Abdalla, Dulcineia Saes Parra, Cole, Jennifer, Monaco, Claudia, Ketelhuth, Daniel F. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099704/ https://www.ncbi.nlm.nih.gov/pubmed/35563591 http://dx.doi.org/10.3390/ijms23095203

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