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Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents

The interaction between tumor surface-expressed PDL1 and immune cell PD1 for the evasion of antitumor immunity is well established and is targeted by FDA-approved anti-PDL1 and anti-PD1 antibodies. Nonetheless, recent studies highlight the immunopathogenicity of tumor-intrinsic PDL1 signals that can...

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Detalles Bibliográficos
Autores principales:	Murray, Clare, Galvan, Eva, Ontiveros, Carlos, Deng, Yilun, Bai, Haiyan, Padron, Alvaro Souto, Hinchee-Rodriguez, Kathryn, Garcia, Myrna G., Kornepati, Anand, Conejo-Garcia, Jose, Curiel, Tyler J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099860/ https://www.ncbi.nlm.nih.gov/pubmed/35563520 http://dx.doi.org/10.3390/ijms23095129

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