Circulating Cell-Free DNA Assessment in Biofluids from Children with Neuroblastoma Demonstrates Feasibility and Potential for Minimally Invasive Molecular Diagnostics

SIMPLE SUMMARY: The invasive nature of surgical biopsies prevents their sequential application to monitor disease. Single biopsies fail to reflect cancer dynamics, intratumor heterogeneity, and drug sensitivities that change over time. Detection and characterization of cell-free circulating tumor DN...

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Detalles Bibliográficos
Autores principales: Lodrini, Marco, Wünschel, Jasmin, Thole-Kliesch, Theresa M., Grimaldi, Maddalena, Sprüssel, Annika, Linke, Rasmus B., Hollander, Jan F., Tiburtius, Daniela, Künkele, Annette, Schulte, Johannes H., Lankes, Erwin, Elgeti, Thomas, Hundsdörfer, Patrick, Astrahantseff, Kathy, Simon, Thorsten, Eggert, Angelika, Deubzer, Hedwig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099910/
https://www.ncbi.nlm.nih.gov/pubmed/35565208
http://dx.doi.org/10.3390/cancers14092080

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