Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish

Members of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can “turn on” and “turn off” signals. Recent studies have shown that this superfamily of proteins ha...

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Autores principales: Urade, Ritesh, Chiu, Yan-Hui, Chiu, Chien-Chih, Wu, Chang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099977/
https://www.ncbi.nlm.nih.gov/pubmed/35563380
http://dx.doi.org/10.3390/ijms23094991
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author Urade, Ritesh
Chiu, Yan-Hui
Chiu, Chien-Chih
Wu, Chang-Yi
author_facet Urade, Ritesh
Chiu, Yan-Hui
Chiu, Chien-Chih
Wu, Chang-Yi
author_sort Urade, Ritesh
collection PubMed
description Members of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can “turn on” and “turn off” signals. Recent studies have shown that this superfamily of proteins has various roles in the process of vascular development, such as vasculogenesis and angiogenesis. Here, we discuss the role of these subfamilies in the development of the vascular system in zebrafish.
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spelling pubmed-90999772022-05-14 Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish Urade, Ritesh Chiu, Yan-Hui Chiu, Chien-Chih Wu, Chang-Yi Int J Mol Sci Review Members of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can “turn on” and “turn off” signals. Recent studies have shown that this superfamily of proteins has various roles in the process of vascular development, such as vasculogenesis and angiogenesis. Here, we discuss the role of these subfamilies in the development of the vascular system in zebrafish. MDPI 2022-04-30 /pmc/articles/PMC9099977/ /pubmed/35563380 http://dx.doi.org/10.3390/ijms23094991 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Urade, Ritesh
Chiu, Yan-Hui
Chiu, Chien-Chih
Wu, Chang-Yi
Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
title Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
title_full Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
title_fullStr Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
title_full_unstemmed Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
title_short Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
title_sort small gtpases and their regulators: a leading road toward blood vessel development in zebrafish
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099977/
https://www.ncbi.nlm.nih.gov/pubmed/35563380
http://dx.doi.org/10.3390/ijms23094991
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