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Relationship between Frailty and Depression in a Population from North-Eastern Romania

(1) Background: In the older population, depression often affects people with chronic medical illnesses, cognitive impairment, or disability. Frailty is another important issue affecting older adults, being difficult to clinically distinguish from frailty in advanced old age. Well-designed intervent...

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Autores principales: Maștaleru, Alexandra, Abdulan, Irina Mihaela, Ștefăniu, Ramona, Lefter, Nicoleta, Sandu, Ioana Alexandra, Pîslaru, Anca Iuliana, Leon-Constantin, Maria Magdalena, Alexa, Ioana Dana, Ilie, Adina Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099999/
https://www.ncbi.nlm.nih.gov/pubmed/35565126
http://dx.doi.org/10.3390/ijerph19095731
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author Maștaleru, Alexandra
Abdulan, Irina Mihaela
Ștefăniu, Ramona
Lefter, Nicoleta
Sandu, Ioana Alexandra
Pîslaru, Anca Iuliana
Leon-Constantin, Maria Magdalena
Alexa, Ioana Dana
Ilie, Adina Carmen
author_facet Maștaleru, Alexandra
Abdulan, Irina Mihaela
Ștefăniu, Ramona
Lefter, Nicoleta
Sandu, Ioana Alexandra
Pîslaru, Anca Iuliana
Leon-Constantin, Maria Magdalena
Alexa, Ioana Dana
Ilie, Adina Carmen
author_sort Maștaleru, Alexandra
collection PubMed
description (1) Background: In the older population, depression often affects people with chronic medical illnesses, cognitive impairment, or disability. Frailty is another important issue affecting older adults, being difficult to clinically distinguish from frailty in advanced old age. Well-designed interventional studies and clinical strategies targeting both frailty and depression are rare or nonexistent. (2) Methods: We realized a retrospective study in which we included a total of 411 patients that were admitted to the Geriatric Clinic from “Dr. C. I. Parhon” Hospital from Iasi for a period of 13 months. The aim of our study was to investigate the relationship between depression and frailty in a geriatric population due to the fact that the quality of life is negatively influenced by both frailty and depression. (3) Results: The prevalence of the depressive symptoms screened by the GDS-15 was 66.7%, with women being more depressed than men. Furthermore, an obvious relationship between depression and the dependence degree in performing daily activities has been observed. In addition, the mean MMSE score decreased with an increasing degree of depression. (4) Conclusions: Our study demonstrates the association between frailty and depression, one of them being a risk factor in the development of the other. A poor acknowledgment of the problem and an underdiagnosis of these conditions are important public health concerns due to the high healthcare costs. Thus, an active primary prevention would be imperiously needed in order to diagnose frailty and depression at an early stage, increasing the quality of life of the elderly and also their successful aging.
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spelling pubmed-90999992022-05-14 Relationship between Frailty and Depression in a Population from North-Eastern Romania Maștaleru, Alexandra Abdulan, Irina Mihaela Ștefăniu, Ramona Lefter, Nicoleta Sandu, Ioana Alexandra Pîslaru, Anca Iuliana Leon-Constantin, Maria Magdalena Alexa, Ioana Dana Ilie, Adina Carmen Int J Environ Res Public Health Article (1) Background: In the older population, depression often affects people with chronic medical illnesses, cognitive impairment, or disability. Frailty is another important issue affecting older adults, being difficult to clinically distinguish from frailty in advanced old age. Well-designed interventional studies and clinical strategies targeting both frailty and depression are rare or nonexistent. (2) Methods: We realized a retrospective study in which we included a total of 411 patients that were admitted to the Geriatric Clinic from “Dr. C. I. Parhon” Hospital from Iasi for a period of 13 months. The aim of our study was to investigate the relationship between depression and frailty in a geriatric population due to the fact that the quality of life is negatively influenced by both frailty and depression. (3) Results: The prevalence of the depressive symptoms screened by the GDS-15 was 66.7%, with women being more depressed than men. Furthermore, an obvious relationship between depression and the dependence degree in performing daily activities has been observed. In addition, the mean MMSE score decreased with an increasing degree of depression. (4) Conclusions: Our study demonstrates the association between frailty and depression, one of them being a risk factor in the development of the other. A poor acknowledgment of the problem and an underdiagnosis of these conditions are important public health concerns due to the high healthcare costs. Thus, an active primary prevention would be imperiously needed in order to diagnose frailty and depression at an early stage, increasing the quality of life of the elderly and also their successful aging. MDPI 2022-05-08 /pmc/articles/PMC9099999/ /pubmed/35565126 http://dx.doi.org/10.3390/ijerph19095731 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Maștaleru, Alexandra
Abdulan, Irina Mihaela
Ștefăniu, Ramona
Lefter, Nicoleta
Sandu, Ioana Alexandra
Pîslaru, Anca Iuliana
Leon-Constantin, Maria Magdalena
Alexa, Ioana Dana
Ilie, Adina Carmen
Relationship between Frailty and Depression in a Population from North-Eastern Romania
title Relationship between Frailty and Depression in a Population from North-Eastern Romania
title_full Relationship between Frailty and Depression in a Population from North-Eastern Romania
title_fullStr Relationship between Frailty and Depression in a Population from North-Eastern Romania
title_full_unstemmed Relationship between Frailty and Depression in a Population from North-Eastern Romania
title_short Relationship between Frailty and Depression in a Population from North-Eastern Romania
title_sort relationship between frailty and depression in a population from north-eastern romania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099999/
https://www.ncbi.nlm.nih.gov/pubmed/35565126
http://dx.doi.org/10.3390/ijerph19095731
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