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Denosumab in Giant Cell Tumor of Bone: Multidisciplinary Medical Management Based on Pathophysiological Mechanisms and Real-World Evidence

SIMPLE SUMMARY: The widely accepted local therapy in extremity giant cell tumor of bone (GCTB) is surgery, in the form of extended intralesional curettage with adequate disease clearance and retention of the limb, wherever possible. Denosumab is a relevant therapy option for advanced GCTB, to benefi...

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Detalles Bibliográficos
Autores principales:	Borkowska, Aneta Maria, Szumera-Ciećkiewicz, Anna, Szostakowski, Bartłomiej, Pieńkowski, Andrzej, Rutkowski, Piotr Lukasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100084/ https://www.ncbi.nlm.nih.gov/pubmed/35565419 http://dx.doi.org/10.3390/cancers14092290

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