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Regulation of Poly-E Motif Flexibility by pH, Ca(2+) and the PPAK Motif

The disordered PEVK region of titin contains two main structural motifs: PPAK and poly-E. The distribution of these motifs in the PEVK region contributes to the elastic properties of this region, but the specific mechanism of how these motifs work together remains unclear. Previous work from our lab...

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Detalles Bibliográficos
Autores principales:	Dassanayake Mudiyanselage, Sudarshi Premawardhana, Gage, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100103/ https://www.ncbi.nlm.nih.gov/pubmed/35563177 http://dx.doi.org/10.3390/ijms23094779

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