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Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression

SIMPLE SUMMARY: The signal transducer and activator of transcription 3 (STAT3) activation correlate with the aggressiveness of pancreatic ductal adenocarcinoma (PDAC). We demonstrated that the autocrine/paracrine interleukin-6 (IL-6) or leukemia inhibitory factor (LIF)/glycoprotein 130 (gp130)/STAT3...

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Detalles Bibliográficos
Autores principales: Sasaki, Norihiko, Hirano, Kazumi, Shichi, Yuuki, Gomi, Fujiya, Yoshimura, Hisashi, Matsushita, Akira, Toyoda, Masashi, Ishiwata, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100112/
https://www.ncbi.nlm.nih.gov/pubmed/35565185
http://dx.doi.org/10.3390/cancers14092055