Cargando…

Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome

(1) Background: Severe fetal hydrothorax can be treated by intrauterine thoracoamniotic shunting (TAS). The aim of this study was to assess perinatal outcome and complication rates of TAS with a novel Somatex intrauterine shunt. (2) Methods: This is a single-center retrospective study of all fetuses...

Descripción completa

Detalles Bibliográficos
Autores principales: Grandt, Joleen, Gottschalk, Ingo, Geipel, Annegret, Gembruch, Ulrich, Simonini, Corinna, Weber, Eva, Berg, Christoph, Müller, Andreas, Strizek, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100171/
https://www.ncbi.nlm.nih.gov/pubmed/35566436
http://dx.doi.org/10.3390/jcm11092312
_version_ 1784706787906158592
author Grandt, Joleen
Gottschalk, Ingo
Geipel, Annegret
Gembruch, Ulrich
Simonini, Corinna
Weber, Eva
Berg, Christoph
Müller, Andreas
Strizek, Brigitte
author_facet Grandt, Joleen
Gottschalk, Ingo
Geipel, Annegret
Gembruch, Ulrich
Simonini, Corinna
Weber, Eva
Berg, Christoph
Müller, Andreas
Strizek, Brigitte
author_sort Grandt, Joleen
collection PubMed
description (1) Background: Severe fetal hydrothorax can be treated by intrauterine thoracoamniotic shunting (TAS). The aim of this study was to assess perinatal outcome and complication rates of TAS with a novel Somatex intrauterine shunt. (2) Methods: This is a single-center retrospective study of all fetuses with hydrothorax treated with TAS using a Somatex shunt between 2014 and 2020. (3) Results: A total of 39 fetuses were included in the study. Mean gestational age at first intervention was 27.4 weeks (range 19–33). Of these, 51% (n = 20) of fetuses had fetal hydrops, which resolved in 65% (13/20) before delivery. The live birth rate was 97% (n = 38), and 74% (n = 29) survived the neonatal period. The rate of postnatal pulmonary complications was high, with 88% of neonates requiring any kind of ventilatory support. There were 23% (n = 9) genetic abnormalities (trisomy 21 and Noonan syndrome). (4) Conclusions: TAS with a Somatex shunt has a high technical success rate, leading to high neonatal survival rates. Pregnancy and neonatal outcome is comparable to TAS for fetal hydrothorax using different shunt types.
format Online
Article
Text
id pubmed-9100171
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91001712022-05-14 Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome Grandt, Joleen Gottschalk, Ingo Geipel, Annegret Gembruch, Ulrich Simonini, Corinna Weber, Eva Berg, Christoph Müller, Andreas Strizek, Brigitte J Clin Med Article (1) Background: Severe fetal hydrothorax can be treated by intrauterine thoracoamniotic shunting (TAS). The aim of this study was to assess perinatal outcome and complication rates of TAS with a novel Somatex intrauterine shunt. (2) Methods: This is a single-center retrospective study of all fetuses with hydrothorax treated with TAS using a Somatex shunt between 2014 and 2020. (3) Results: A total of 39 fetuses were included in the study. Mean gestational age at first intervention was 27.4 weeks (range 19–33). Of these, 51% (n = 20) of fetuses had fetal hydrops, which resolved in 65% (13/20) before delivery. The live birth rate was 97% (n = 38), and 74% (n = 29) survived the neonatal period. The rate of postnatal pulmonary complications was high, with 88% of neonates requiring any kind of ventilatory support. There were 23% (n = 9) genetic abnormalities (trisomy 21 and Noonan syndrome). (4) Conclusions: TAS with a Somatex shunt has a high technical success rate, leading to high neonatal survival rates. Pregnancy and neonatal outcome is comparable to TAS for fetal hydrothorax using different shunt types. MDPI 2022-04-21 /pmc/articles/PMC9100171/ /pubmed/35566436 http://dx.doi.org/10.3390/jcm11092312 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Grandt, Joleen
Gottschalk, Ingo
Geipel, Annegret
Gembruch, Ulrich
Simonini, Corinna
Weber, Eva
Berg, Christoph
Müller, Andreas
Strizek, Brigitte
Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome
title Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome
title_full Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome
title_fullStr Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome
title_full_unstemmed Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome
title_short Intrauterine Thoracoamniotic Shunting of Fetal Hydrothorax with the Somatex Intrauterine Shunt: Intrauterine Course and Postnatal Outcome
title_sort intrauterine thoracoamniotic shunting of fetal hydrothorax with the somatex intrauterine shunt: intrauterine course and postnatal outcome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100171/
https://www.ncbi.nlm.nih.gov/pubmed/35566436
http://dx.doi.org/10.3390/jcm11092312
work_keys_str_mv AT grandtjoleen intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT gottschalkingo intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT geipelannegret intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT gembruchulrich intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT simoninicorinna intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT webereva intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT bergchristoph intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT mullerandreas intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome
AT strizekbrigitte intrauterinethoracoamnioticshuntingoffetalhydrothoraxwiththesomatexintrauterineshuntintrauterinecourseandpostnataloutcome